FERMing Up the Synapse
نویسندگان
چکیده
منابع مشابه
Pumping Up the Synapse
Synchronized control of excitatory and inhibitory synapse maturation is crucial for normal brain wiring, while its dysfunction leads to neurodevelopmental disorders, including autism. A paper in this issue of Neuron identified a novel role for the KCC2 pump, also responsible for the GABAergic synapse developmental switch, in regulating spiny excitatory synapse maturation, implicating it in the ...
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in the presynaptic cell and of neurotransmitter receptors in the postsynaptic cell is believed to be one of the earliest steps leading to synapse formation (Sanes and Lichtman, 1999). An important role in synapse organization and stabilization is played by PSD95/Dlg/ZO-1 Eph receptor tyrosine kinases and their ligands, the (Garner et al., 2000). ephrins, have attracted considerable interest in ...
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ژورنال
عنوان ژورنال: Immunity
سال: 2001
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(01)00237-0